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Monoclonal antibodies targeting IL-1 beta reduce biomarkers of atherosclerosis in vitro and inhibit atherosclerotic plaque formation in Apolipoprotein E-deficient mice

V Bhaskar, J Yin, AM Mirza, D Phan, S Vanegas... - Atherosclerosis, 2011 - Elsevier OBJECTIVE: Atherosclerosis is a condition that is increasingly contributing to worldwide mortality through complications such as stroke and myocardial infarction. IL-1β plays multiple direct, local roles in the formation and stability of the atheroma by eliciting the ...

Cardiac MRI findings in patients with Myocarditis

DO h-Ici, Y Louvard, T Unterseeh... - Journal of ..., 2011 - Springer Background Cardiac Magnetic Resonance Imaging (CMR) is a . The recent conjoint report of the American College of Cardiol- ogy and the SCMR has classified its use as appropriate or Class A Indication in inflammatory cardiomyopathy. The aim of this study was to ...

Therapeutic Potential for HDAC Inhibitors in the Cardiovascular System

TA Mc Kinsey - Annual Review of Pharmacology and ..., 2012 - Abstract Reversible protein acetylation provides a central mechanism for controlling gene expression and cellular signaling events. Two pharmacological inhibitors of protein deacetylation are currently approved for the treatment of human cancer, and numerous ...

Percutaneous Approaches to Valvular Heart Disease After Previous Cardiac Surgery

JM Stulak... - Redo Cardiac Surgery in Adults, 2012 - Springer While open surgical correction is the best treatment for most patients with valvular heart disease, there have been recent technical advances that permit percutaneous approaches to valve replacement and valve repair in selected circumstances. The most widely ... [CITATION] Does aortic stiffness improve the prediction of coronary heart disease in elderly? The Rotterdam Study GC Verwoert, SE Elias-Smale, D Rizopoulos... - Journal of Human ..., 2012

Early Findings on Brain Computed Tomography and the Prognosis of Post Cardiac Arrest Syndrome: Application of the Score for Stroke Patients

H Sugimori, T Kanna, K Yamashita, T Kuwashiro... - Resuscitation, 2012 - Elsevier Aim To examine whether early findings of the brain CT evaluated by the modified Alberta stroke programme early CT (m-ASPECT) score is useful for determining the prognosis of post-cardiac arrest syndrome (PCAS) patients or not.
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